Cannabinoid Clinic: CBDA

Updated: 4 days ago

Welcome to Cannabinoid Clinic, an education project powered by Higher Learning LV. This series provides cannabis and hemp industry professionals with easily digested cannabinoid profiles that ask little of your time—but provide plenty of science-based information.


There are two categories of cannabinoids: Phytocannabinoids and endocannabinoids. Phytocannabinoids are those produced by cannabis/marijuana/hemp, while endocannabinoids are made by the human body. This series covers both.

CBDA molecular structure


What is CBDA?

Cannabidiolic acid (CBDA) is the acidic precursor to cannabidiol, or CBD. CBDA is one of the most common terpenes produced by cannabis and hemp. It is derived from the "mother of all cannabinoids," cannabigerolic acid (CBGA), which also produces the important cannabinoids tetrahydrocannabinolic acid (THCA) and cannabichromenic acid (CBCA).


Although not psychoactive, research has revealed that CBDA delivers a wide range of potential medicinal benefits, including anti-inflammatory and anti-seizure properties. If decarboxylated with heat or a flame, CBDA morphs into CBD. This occurs when cannabis consumers vaporize or smoke the loose-leaf flowers of the plant.


CBDA Fast Facts

  • Role: Produces CBD

  • Biosynthetic pathway: CBGA > CBDA > CBD

  • Psychoactivity: Non-psychoactive

  • Acidic precursor: CBGA

  • Boiling point: 266° F

  • Primary medical benefits: Anti-inflammatory, antidepressant, and anticonvulsive



CBDA Medicinal Benefits

The primary potential medicinal benefits of CBDA are found in its anti-inflammatory and anticonvulsant properties. However, it has also demonstrated the ability to fight pain.


Like other cannabinoids, CBDA has also demonstrated anti-nausea properties, making it of potential benefit to those undergoing chemotherapy, including patients with HIV/AIDS, cancer, and Crohn's disease.


How to Get CBDA

Juicing the leaves of mature cannabis plants is one of the best ways to get CBDA into your body. However, many patients and consumers do not have access to the raw leaves of the plant. Such consumers can create infused food with loose-leaf hemp flower that they purposefully do not decarboxylate.


Some companies sell products like tinctures, capsules, and topical products that provide CBDA.


Like what you just read? Check out our new Cannabis for Cancer Hub that features links to all of our articles about marijuana for cancer.

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