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Cannabinoid Clinic: Delta-10 THC

Updated: Dec 7, 2022

Welcome to Cannabinoid Clinic, an education project powered by Higher Learning LV. This series provides cannabis and hemp industry professionals with easily digested cannabinoid profiles that ask little of your time—but provide plenty of science-based information.


There are two categories of cannabinoids: Phytocannabinoids and endocannabinoids. Phytocannabinoids are those produced by cannabis/marijuana/hemp, while endocannabinoids are made by the human body. This series covers both.

Delta-10 THC molecular structure


What is Delta-10 THC?

The version of THC that differentiates hemp and cannabis, the measure of which has determined the market value of cannabis flowers and related products for decades, is delta-9 THC. However, a variety of analogs of this infamous molecule exist. These include THCA (no psychoactivity), delta-8 THC (about two-thirds the psychoactivity of the delta-9 isomer), and THCV (the varin version that delivers psychoactivity, but only in relatively potent doses).


THC molecular analogs include THCA (no psychoactivity), delta-8 THC (about two-thirds the psychoactivity of delta-9), and THCV (delivers psychoactivity, but only in relatively potent doses).

Like delta-8 THC, some wellness professionals and doctors who recommend cannabinoids for their patients prefer delta-10 because it conveys lower psychoactivity than delta-9, helping prevent increased anxiety or panic attacks—especially in consumers prone to these reactions.

Delta-10 THC is naturally occurring, but has been dubbed an "artificial cannabinoid" because it is found in only trace volumes in nature (with many plants containing no delta-10). Unfortunately, this had led to the emergence of an urban legend concerning delta-10 that incorrectly states that it does not occur in nature. Modern manufacturing processes, however, offer the ability to produce the molecule in volume by converting closely related cannabinoids.


Delta-10 THC is naturally occurring, but has been dubbed an "artificial cannabinoid" because it is found in only trace volumes in nature.

Some industry professionals believe that, during testing, delta-10 THC is commonly misidentified as similar cannabinoids, including CBC. "A lot of people had been seeing this mystery compound show up as a minor component on their distillate COAs [Certificates of Analysis], but they thought it was CBC," said Josh Jones, an organic chemist in California.


Delta-10 THC Fast Facts

  • Role: THC isomer

  • Biosynthetic pathway: CBD > delta-10 THC

  • Psychoactivity: Psychoactive

  • Acidic precursor: n/a

  • Boiling point: n/a

  • Primary medical benefits: Anti-inflammatory and anticonvulsant

Delta-10 THC Medicinal Benefits

Research regarding the potential medical benefits of delta-10 THC is almost nonexistent, with much more data available for mainstream cannabinoids such as CBD, CBG, and delta-9 THC. However, a combination of research data and anecdotal testimonies have shown that delta-10 may provide a variety of benefits, similar to other THC isomers.


Anecdotal reports indicate that delta-10 may be more energizing than its chemical cousin delta-8 THC. In other words, delta-10 is reported to be more indica-like, while delta-10 more resembles sativa cultivars. It may be of help to those with glaucoma, depression, and anxiety (but must be dosed correctly to obtain favorable results) and may also reduce the nausea that results from cancer chemotherapy.


In other words, delta-10 is reported to be more indica-like, while delta-10 more resembles sativa cultivars.

Similar to delta-8 and delta-9 THC, delta-10 may produce minor negative side effects, including dry eyes, dry mouth, or increased anxiety. However, this alt cannabinoid has been noted to feature an acceptable safety profile. Even potent doses of this cannabinoid are relatively safe for consumption.


Like with other cannabinoids, closely related isomers of delta-9 THC often feature similar efficacies. Those that result in psychoactivity may, in potent doses and especially when consumed by those with little experience, produce anxiety or even panic attacks.


How to Get Delta-10 THC

Like delta-8, HHC, and THC-O acetate, delta-10 THC is readily available in many areas of the United States in the form of 510 vape carts, gummies, and a variety of edibles. Delta-10 is most commonly obtained from hemp-derived CBD (like delta-8 THC).


Many products claiming to contain only delta-10 THC often also contain delta-8 due to the chemical difficulty of isolating only delta-10.


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