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Cannabis for Cancer: Cannabinoids for Colorectal Cancer

Welcome to homework assignment CCS 1.4 of the Cannabis for Cancer Seminar from Higher Learning LV. This assignment teaches students the latest peer-reviewed scientific research about cannabis for cancer. This study summary examines the therapeutic application of cannabinoids—particularly CBD and delta-9 THC—for colorectal cancer and the cachexia and muscle atrophy that is associated with the majority of incidences of this cancer, particularly advanced cases.

When you complete this homework assignment, simply click the link at the bottom of the article to return to the master page for this seminar.


A May 2023 in vivo rodent study entitled "The Protective Effect of Cannabinoids Against Colorectal Cancer Cachexia Through Modulation of Inflammation and Immune Responses" that was published in the journal Biomedicine & Pharmacotherapy explored the potential efficacy of cannabinoids such as delta-9 THC in the treatment of colorectal cancer, with a focus on the cachexia that is so prevalent in colorectal cancer patients.

The study explained that cancer cachexia is a syndrome that is both devastating and that affects more than half of all cancer patients (50-80 percent). Cancer cachexia is responsible for up to 20 percent of cancer-related deaths and involves skeletal muscle wasting, a condition that cannot be reversed and may be caused by abnormal protein synthesis. It is most commonly observed in patients who have gastrointestinal cancers and is rare in those with hematological cancers of the blood.

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