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Core Cannabis Course: 2-AG

Updated: Mar 24, 2023

Welcome to homework assignment CCC 1.9 of the Core Cannabis Course from Higher Learning LV. This assignment teaches students about the endocannabinoid 2-AG. This cannabinoid is involved in the maintenance of the endocannabinoid system and its overall health. Some researchers hypothesize that some cannabinoids—including CBD—mimic the behavior of 2-AG (likewise, the phytocannabinoid delta-9 THC is said to mimic the endocannabinoid anandamide, the subject of the following homework assignment).

When you complete this assignment, simply click the link at the bottom of the article to return to the master page for this course.


What is 2-AG?

The two major endocannabinoids produced by the human endocannabinoid system (ECS) are 2-AG and anandamide. 2-AG is short for 2-arachidonoylglycerol and was discovered in 1994 by Japanese researchers at Teikyo University. Raphael Mechoulam and his student Shimon Ben-Shabat at Hebrew University first isolated 2-AG from the gut of a dog in 1995, three years following the discovery of the endocannabinoid anandamide.

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