Deep Dive: Cannabidiol Dosing

Cannabidiol (CBD) extracts—such as those derived from hemp or cannabis—are available to consumers in a variety of form factors for different consumption avenues. One of the most popular is the tincture, a liquid preparation based in alcohol or oil that is applied sublingually (under the tongue).

Because a tincture is absorbed sublingually, the onset of efficacy of cannabinoid- and terpene-based medicines delivered via this route is considerably faster than eating the same molecules (an ingestion route that requires about two hours for onset). The bioavailability onset of sublingual preparations like tinctures, on the contrary, is 10 to 20 minutes. For pain and anxiety patients, the difference between 20 minutes and two hours is significant.

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