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Common Responses to Marijuana in Humans. On August 29, 2023, the Department of Health and Human Services (HHS) send a letter to the Drug Enforcement Agency (DEA) recommending that it reschedule cannabis (marijuana) from Schedule I to Schedule III. Read our comprehensive 3,800-word analysis of cannabis rescheduling to Schedule III here.
As much excitement and media attention as the letter created within the cannabis industry, the issue over which thought leaders obsessed was the shift to Schedule III. Unfortunately the letter itself couldn't be analyzed because it was not released to the public.
That all changed in mid-January when the HHS published the full 252-page letter that was sent to the DEA last August. Among those hundreds of densely scientific pages, the letter's authors included a unique list of "common responses to marijuana in humans," listed below.
Common Responses to Marijuana in Humans
Positive Subjective Responses
Euphoria
Pleasurable "rush" or "buzz"
Merriment
Happiness
Exhilaration
Sedative Responses
Sedation
Drowsiness
Relaxation
Changes in sleep
Anxiety and Negative Responses
Panic attack
Fearfulness
Agitation
Paranoia
Restlessness
Dysphoria
Perceptual Changes
Hallucinations
Feelings seem stronger
Spiritual enhancement
Changes in time perception
Changes in perception (sight, sound, taste, smell, touch)
Psychiatric, Social, and Cognitive Changes
Illusions
Delusions
Depersonalization
Heightened imagination
Disinhibition
Emotional lability
Memory and concentration impairment
Disorganized thinking
Impaired judgment
Confusion
Increased sociability
Talkativeness
Physiological Responses
Tachycardia
Facial flushing
Tremor
Dizziness
Increased appetite, especially for sweet and fatty foods
Reduced coordination
Ataxia
View the original HHS letter.
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