Bisabolol Research

Updated: May 7

Bisabolol, also called levomenol, was first isolated in 1951 from the essential oil of chamomile (some examples of which contain up to 50 percent α-bisabolol in weight by volume). In isolation, this terpene conveys a subtle aroma that is floral in nature, with possible hints of nut or pepper.

German chamomile


In addition to cannabis, it is made by the Candeia tree, German chamomile, and sage. This terpene has been employed in various topical treatments and cosmetics for centuries based on its reputed ability to heal skin.


A 2015 study entitled "Evaluation of Bisabolol as a Promising Agent Against Leishmania Amazonensis" that was published in the journal Experimental Parasitology investigated the potential medicinal efficacy of the terpene bisabolol for the parasitic disease found in tropical and subtropical regions, including Southern Europe.


The study concluded that bisabolol is a promising treatment for leishmanial because it "can act against the promastigote forms and is able to penetrate the cell."

The study concluded that bisabolol is a promising treatment for leishmanial because it "can act against the promastigote forms and is able to penetrate the cell."

The bisabolol molecule


A 2004 study entitled "α-Bisabolol, a Nontoxic Natural Compound, Strongly Induces Apoptosis in Glioma Cells" that was published in the journal Biochemical and Biophysical Research Communications explored the ability of bisabolol to kill a common type of brain tumor called a glioma.


The peer-reviewed study explored the ability of bisabolol to kill a common type of brain tumor called a glioma. Johns Hopkins Medicine estimates that gliomas constitute "about 33 percent of all brain tumors."

The peer-reviewed study explored the ability of bisabolol to kill a common type of brain tumor called a glioma. Johns Hopkins Medicine estimates that gliomas constitute "about 33 percent of all brain tumors."


The research found that bisabolol exhibited an extremely high efficacy against the tumor cells. "Glioma cells treated with high concentration of α-bisabolol (10 μM) resulted in a 100 percent cell death," reported the researchers. The study’s authors concluded, "α-bisabolol may be considered [to be] a novel compound [that is] able to inhibit glioma cell growth and survival."


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